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Mueller matrices provide a complete characterization of
the optical polarization properties of biological tissue. A
polarization-sensitive optical coherence tomography (OCT) system was
built and used to investigate the optical polarization properties of
biological tissues and other turbid media. The apparent degree of
polarization (DOP) of the backscattered light was measured with both
liquid and solid scattering samples. The DOP maintains the value of
unity within the detectable depth for the solid sample, whereas the DOP
decreases with the optical depth for the liquid sample. Two-dimensional
depth-resolved images of both the Stokes vectors of the backscattered
light and the full Mueller matrices of biological tissue were measured
with this system. These polarization measurements revealed some tissue
structures that are not perceptible with standard OCT.
Selected publications:
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J. Ai and L.-H. Wang,
"Spectral-domain optical coherence tomography: Removal of
autocorrelation using an optical switch," Applied Physics
Letters 88 (11), 111115 (Mar. 2006).[PDF]
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S. Jiao, W. Yu, G. Stoica, and
L.-H. Wang, "Optical-fiber-based Mueller optical coherence
tomography," Optics Letters, 28 (14), 1206-1208 (July 2003).[PDF]
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S. Jiao and L.-H. Wang
"Two-dimensional depth-resolved Mueller matrix of biological
tissue measured with double-beam polarization-sensitive
optical coherence tomography," Optics Letters 27 (2),
101–103 (2002). [PDF]
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G. Yao and L.-H. Wang,
"Two-dimensional depth-resolved Mueller matrix characterization
of biological tissue by optical coherence tomography," Optics
Letters 24, 537-539 (1999). [PDF]
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G. Yao, and L.-H. Wang, "Monte
Carlo simulation of optical coherence tomography in homogeneous
turbid media," Physics in Medicine and Biology, 44, 2307-2320
(1999). [PDF]
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